Daye Research Makes the Case for Adding the Vaginal Microbiome to Cervical Cancer Risk Models | Femtech Insider

Daye Research and academic collaborators argue cervical cancer screening is missing the vaginal microbiome as a risk signal.
Lactobacillus-dominant vaginal microbiomes are described as protective.
Dysbiotic, anaerobe-rich microbiomes are linked to HPV persistence and higher-grade cervical disease.
No validated cervical cancer risk model in current clinical use includes vaginal microbiota.
The paper proposes measuring the microbiome from the same self-collected sample used for HPV screening.
Daye’s Diagnostic Tampon is presented as a way to add microbiome data without extra burden for patients or labs.
The authors frame cervical cancer risk as a network of factors, not HPV alone.
Key factors in that network include the virus, immune system, vaginal environment, vaccination status, and behavior.
The paper argues the central question is whether the vaginal environment supports or inhibits viral persistence.

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